Rheumatoid arthritis (RA) is a chronic systemic disease1 that affects primarily the lining of the joints of the body and usually the smaller joints in the hands and feet. Other joints such as shoulders, knees and neck can also be affected. RA is the most common auto-immune disease in Australia, affecting about 2% of the Australian population. RA is the second most common arthritis after osteoarthritis (OA) and the most common type of inflammatory arthritis. The onset of RA usually occurs between the ages of 40 and 50 years. About three times more women than men are affected by RA.
RA is an auto-immune disease which means that your body sees your own healthy tissue as something foreign and potentially a threat or a danger. The immune system then targets the lining of the joints, causing inflammation associated with joint pain and swelling, with the potential for joint and bone damage. Because RA is a systemic disease, it can also affect other body systems, such as your eyes, lungs and blood vessels. The cause of RA is unknown, however there are contributory risk factors, including genetic factors such as a family history of RA, and environmental factors including smoking, gum disease and obesity.
Early diagnosis and appropriate treatment can relieve symptoms, prevent or delay joint damage and ensure that people with RA can continue to lead an active life1.
What symptoms and signs suggest rheumatoid arthritis?
There are a number of symptoms that may suggest RA1. These vary from person to person and over the course of the disease. The most common symptoms of RA include:
- joint pain, swelling and stiffness usually affecting the wrists, fingers and toes on both sides. Other joints including the shoulders, elbows, knees, ankles and the neck may be affected
- pain that is typically worse after rest or early in the morning
- joint stiffness in the morning (>30 minutes) and stiffness after rest
- feeling generally unwell and losing weight
- reduced ability to do daily activities important to you including work, home and recreational interests
- skin lumps (nodules), eye dryness or redness
Fatigue or tiredness is very common in RA. You may find that resting more does not help this feeling. Sometimes trying to exercise in the hope you'll improve may make the feeling worse and this can be disheartening. If you are in pain and feeling anxious, depressed, and not sleeping well, this feeling of fatigue can be very pronounced. You might find the pacing and goal setting or approaching pain management modules helpful.
If you suspect that you may have RA, we recommend you consult your doctor to discuss the potential for further investigations to diagnose RA and guide your management. Your doctor will arrange blood tests and possibly x-rays and other imaging. Based on these results, you may be referred to a specialist called a rheumatologist who will help guide you regarding further RA management.
What happens when I am diagnosed with rheumatoid arthritis?
Diagnosing RA early and starting the right treatment at the right time will result in a better outcome. The rheumatologist will ask you about your symptoms, perform a thorough examination and request further investigations in order to make decisions about your diagnosis, management and the role of medications. He or she may also recommend visits to relevant health professionals (such as a rheumatology nurse, physiotherapist, occupational therapist, and podiatrist).
Nurses and physiotherapists play a large role in helping people with RA manage their disease symptoms and maintain participation in daily work, home and recreational activities. The rheumatology nurse can provide emotional support as well as giving you information on your disease, medications and RA support groups. The physiotherapist with skills in RA management can advise you about an appropriate exercise programme and activities to maintain joint function and muscle strength and to help manage pain. The occupational therapist can provide splints for inflamed or deformed hand joints and can advise you about aids to help you to function better as well as modifications at work and at home. The podiatrist can advise you on appropriate footwear and supportive insoles to relieve foot pain and prevent or support foot deformities. You may also find clinical psychology helpful especially if you experience low mood, persistent pain or have difficulties coping with your RA. You can check out the approaching Pain management module: this gives you some practical tips for managing mood and access to some online training modules.
What about treatments?
If you do have RA, you need an individually developed treatment plan2. Both pharmacological (medicines) and non-pharmacological3 management approaches (for example, self management including managing fatigue, joint health, stretching and exercising) are important4. There is good evidence that being educated about your RA, and working with your health team to develop a self-management plan including aerobic exercise (exercise that makes you 'huff and puff'), muscle strengthening and stretching exercises that suit you, means better outcomes4. You might find the movement and pain management module, or pacing and goal setting activities such as yoga and mindfulness meditation may also be very beneficial in helping you manage your mental wellbeing.
You will need specific medications that slow the disease process5. These are known as disease-modifying anti-rheumatic drugs (DMARDs). DMARDs are the mainstay of treatment for RA and are most effective when initiated early in the disease course6. There are some side effects and these are well documented3 so you can discuss them with your doctor. Women who wish to become pregnant and/or breastfeed often need to modify their medications to optimise the health of their baby. DMARDs control joint inflammation so that your symptoms of joint pain, swelling and stiffness improve. They also improve your functional ability and help prevent joint damage. Paracetamol and anti-inflammatory medications can improve joint pain and swelling, however these do not slow the disease process.
What about symptom 'flares'?
There may be times when some of your symptoms are particularly bad - your joints may swell more, feel more painful and may be warm to touch. This is known as a 'flare'. There may be several reasons for this, including:
- the disease is progressing and your current levels of medication are not enough to control it or
- you may have had a busy weekend and over done things
It is important that you see your doctor or rheumatologist as early as possible. Your doctor or rheumatologist may need to change your medication(s). It is also important that you modify (not cease) your physical activity during a flare to allow your body to recover.
If you're experiencing pain related to RA or are concerned about RA, we recommend our Medical Self-Check through our pain self-checks page to help you screen for conditions that may suggest you should consult a Health Professional. Alternatively, if you want to talk to someone about RA, please seek further assistance.
- Rudan I, Sidhu S, Papana A, et al. Prevalence of rheumatoid arthritis in low- and middle-income countries: A systematic review and analysis. J Glob Health 2015; 5(1): 010409. [PubMed]
- Stoffer MA, Smolen JS, Woolf A, et al. Development of patient-centred standards of care for rheumatoid arthritis in Europe: the eumusc.net project. Annals of the rheumatic diseases 2014; 73(5): 902-5. [PubMed]
- Ramiro S, Gaujoux-Viala C, Nam JL, et al. Safety of synthetic and biological DMARDs: a systematic literature review informing the 2013 update of the EULAR recommendations for management of rheumatoid arthritis. Annals of the rheumatic diseases 2014; 73(3): 529-35. [PubMed]
- Brosseau L, Rahman P, Poitras S, et al. A systematic critical appraisal of non-pharmacological management of rheumatoid arthritis with Appraisal of Guidelines for Research and Evaluation II. PloS one 2014; 9(5): e95369. [PubMed]
- Smolen JS, Landewe R, Breedveld FC, et al. EULAR recommendations for the management of rheumatoid arthritis with synthetic and biological disease-modifying antirheumatic drugs: 2013 update. Annals of the rheumatic diseases 2014; 73(3): 492-509. [PubMed]
- Nam JL, Ramiro S, Gaujoux-Viala C, et al. Efficacy of biological disease-modifying antirheumatic drugs: a systematic literature review informing the 2013 update of the EULAR recommendations for the management of rheumatoid arthritis. Annals of the rheumatic diseases 2014; 73(3): 516-28. [PubMed]